The history and the present conditions of the occupational bladder cancer in our country

PURPOSE: We examined the history and the present conditions of the occupational bladder cancer of our country and a chemical carcinogenesis study career of the bladder cancer. OBJECT AND METHOD: We performed consideration from literatures mainly on document and Ministry of Health, Labor and Welfare, Labor Standards Bureau, Accident compensation element document and documents of Association of Formation Product Industry. RESULT: Production of aromatic amine was started in about 1920 in our country, and the first occupational bladder cancer case was reported in 1940. It arrived at the greatest amount of production time of aromatic amine caused by Communist China Trade in 1955. The production, the import of benzidine and 2-naphthylamine were prohibited in 1972 by Safe Hygiene Method Official Announcement. During this time, 3,310 people were exposed by these materials, and the occupational bladder cancer of 357 people was registered by 1985. A number authorized from 1976 through 2006 that Workmen's comp was started is 341 cases of urinary tract system tumors by duties exposed to benzidine, 150 cases of urinary tract system tumors by duties exposed to 2-naphthylamine and one case of urinary tract tumors by o-dianisidine in total 492 cases. The occupational urinary tract cancer patient almost reaches a retirement age, and it is thought that they reach the end in about 2025. CONCLUSION: We reported the history and the present conditions of the occupational bladder cancer which occurred from 3,310 people of aromatic amine revelation in our country and we commented on a trend of the recent occupational bladder cancer for consideration from literatures.