Preparation of Celecoxib Tablet by Hot Melt Extrusion Technology and Application of Process Analysis Technology to Discriminate Solubilization Effect

Ilhwan Hwang,Vanamane Renuka,Ju-Hyun Lee,Kwon Yeon Weon,Chin-Yang Kang,Beom-Jin Lee,Jun-Bom Park

Preparation of Celecoxib Tablet by Hot Melt Extrusion Technology and Application of Process Analysis Technology to Discriminate Solubilization Effect

2020

Ilhwan Hwang
Vanamane Renuka
Ju-Hyun Lee
Kwon Yeon Weon
Chin-Yang Kang
Beom-Jin Lee
Jun-Bom Park

AbstractThe aim of this study was to prepare various types of solid dispersions (SDs) by the hot-melt extrusion technique. Next, process analytical technology (PAT) such as Fourier transform-infrar...

Keywords:

Chemistry
process analysis
Solubilization
hot melt
Process analytical technology
Chromatography
Extrusion
Dispersion (chemistry)

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