S1133 MELD, MELD-Na, and MELD-Albumin Scores as Predictors of Mortality in Patients With SARS-CoV-2: An Uncanny Relationship During Troubling Times

INTRODUCTION: Coronavirus disease 2019 (SARS-CoV-2) is an ongoing outbreak, capable of causing severe acute respiratory disease Patients diagnosed with SARS-CoV-2 have significant morbidity and mortality The model for end-stage liver disease (MELD) score, MELD-Na and MELD-Albumin scores are used to predict mortality in patients with liver disease METHODS: This is a single center retrospective cohort study of patients diagnosed with 2019 Novel Coronavirus (SARS-CoV-2) between March of 2020 and May of 2020 The primary outcome includes all cause in-hospital mortality Our study aimed to validate the utility of the various scores in predicting mortality in patients diagnosed with SARS-CoV-2 RESULTS: MELD, MELD-Na and MELD-Albumin was evaluated in a cohort of 71 patients The analysis included 31/71 (43 66%) men with a mean age of 66±16 years The median MELD, MELD-Na and MELD-Albumin scores were 28 8, 27 9 and 30 2 respectively A cutoff value of 30 was assigned to stratify patients into low and high groups Mortality rates for patients with a low MELD, MELD-Na and MELDAlbumin score (, 30) was 20 45%, 18 6% and 15 15% respectively Mortality rates for patients with a high MELD, MELD-Na and MELD-Albumin score (>30) was 45%, 47 62% and 41 94% respectively All three scores can be used to predict mortality in patients who developed PCR-positive SARS-CoV-2 CONCLUSION: MELD, MELD-Na and MELD-Albumin are valid prognostic scores that can be used as good predictors of mortality in patients with PCR-confirmed SARS-CoV-2 MELD-Albumin appears to have the highest predictive potential (Table Presented)