Impact of CGA in therapeutic decisions: ELDERLY trial.

759 Background: Based on results from phase III clinical trials chemotherapy treatment benefit in patients ≥70 years old with stage III and IV colorectal cancer (CRC III-IV) is a subject in question. The ELDERLY trial aims to explore in a pilot program viability and convenience of an evidence based protocol for Comprehensive Geriatric Asessment (CGA) as well as the contribution of further evaluations. Methods: Patients ≥70 years old with CRC III-IV were prospectively and consecutively included. After initial treatment recommendation was made, study protocol for CGA (functional, nutritional, cognitive, social, psychological, and comorbidities) was carried out. Based on CGA, early death risk prediction model and chemotherpy toxicity risk stratification subsequent final treatment recommendation was obtained. Follow up of patients and comparison to historical controls is underway. Results: 20 patients (10 CRC III, 10 CRC IV), median age 79.2 years (71-85), 65% males, were included. ECOG PS was: 0 in 35% of pa...