Outcomes of endoscopic ultrasound-guided biliary drainage: A systematic review and meta-analysis:

BackgroundSuccess and event rates of endoscopic ultrasound (EUS)-guided biliary drainage vary with techniques, and results from different studies remain inconsistent.ObjectiveWe conducted a proportion meta-analysis to evaluate the efficacy and safety of EUS-guided biliary drainage and compare the outcomes of current procedures.MethodsWe searched MEDLINE, Embase, Cochrane and Web of knowledge to identify studies reporting technical success, clinical success and complication rates of EUS-guided biliary drainage techniques to estimate their clinical and technical efficacy and safety.ResultsWe identified 17 studies including a total of 686 patients. The overall clinical success and technical success rates were respectively 84% confidence interval (CI) 95% (80–88) and 96% CI 95% (93–98) for hepaticogastrostomy, and respectively 87% CI 95% (82–91) and 95% CI 95 (91–97) for choledochoduodenostomy. Reported adverse event rates were significantly higher (p = 0.01) for hepaticogastrostomy (29% CI 95% (24–34)) compa...