Long-term outcome after early repair of complete atrioventricular septal defect in young infants

Abstract Objective The long-term outcome after repair of cAVSD in young infants is still not fully understood. The objective of this study was to evaluate data after repair for cAVSD over a 25-year period in order to assess survival and identify risk factors for LAVV-related reoperations. Methods A total of 304 consecutive patients underwent surgical correction for cAVSD between April 1993 and October 2018. The results for young infants ( 3 months old; n=249; mean age 5.1±5.2 months). Mean follow-up was 13.2±7.8 years (median 14.0 years; IQR 7.0‒20.0). The Kaplan-Meier method was used to assess overall survival and freedom from LAVV-related reoperation. Results Overall 30-days mortality was 1.0% (3/304) with no difference between young and older infants (p=1.0). Overall survival in the total population at 20-year follow-up was 95.1% (±1.3%). Independent risk factors for poor survival were the presence of an additional VSD (p=0.042), previous coarctation of the aorta (p Conclusions Our data demonstrated that excellent long-term survival could be achieved with early repair for cAVSD, and the need for reoperations due to LAVV-regurgitation was low. In our opinion, primary correction in patients