Knockdown of Forkhead box A1 suppresses the tumorigenesis and progression of human colon cancer cells through regulating the phosphatase and tensin homolog/Akt pathway.

Jie Pan,Zongbin Xu,Meifang Xu,Xiaoyan Lin,Bingqiang Lin,Mengxin Lin

Knockdown of Forkhead box A1 suppresses the tumorigenesis and progression of human colon cancer cells through regulating the phosphatase and tensin homolog/Akt pathway.

2020

Jie Pan
Zongbin Xu
Meifang Xu
Xiaoyan Lin
Bingqiang Lin
Mengxin Lin

BackgroundThis study aimed to evaluate the role and the underlying mechanisms of Forkhead box A1 (encoded by FOXA1) in colon cancer.MethodsWe analyzed FOXA1 mRNA and protein expression in colon can...

Keywords:

Tensin
Gene knockdown
Carcinogenesis
PI3K/AKT/mTOR pathway
Messenger RNA
Colorectal cancer
FOXA1
Phosphatase
Medicine
Cancer research

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