Abstract 12932: An Epigenetic Upregulation of Dynamin 2, a Regulator of Mitochondrial Fission, Promotes Human and Experimental Pulmonary Arterial Hypertension

Asish Das Gupta,K.H. Chen,Lian Tian,Danchen Wu,Jeffrey Mewburn,Patricia D.A. Lima,Stephen L. Archer

Abstract 12932: An Epigenetic Upregulation of Dynamin 2, a Regulator of Mitochondrial Fission, Promotes Human and Experimental Pulmonary Arterial Hypertension

2021

Asish Das Gupta
K.H. Chen
Lian Tian
Danchen Wu
Jeffrey Mewburn
Patricia D.A. Lima
Stephen L. Archer

Introduction: Increase in mitotic fission in pulmonary arterial smooth muscle cells (PASMC) contributes to the obstructive vasculopathy in pulmonary arterial hypertension (PAH). PAH’s fissogenic ph...

Keywords:

Cancer research
Regulator
Downregulation and upregulation
Mitosis
Pulmonary hypertension
Mitochondrion
Mitochondrial fission
Dynamin
microRNA
Medicine

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