Involvement of the HLXB9 Homeobox Gene in Currarino Syndrome

This work has been supported by “Fondazione Telethon Italia” grant 297/bi, the Italian Ministry of Health, “Ricerca Finalizzata, 1996,” and the Medical Research Council of Canada (MRC). We are grateful to patients and families who provided samples for our analysis. The authors would also like to acknowledge Peter Heutink, Carol Stayton, Massimiliano Agnelli, Silvia Presi, Elena Rossi, Roberta Cinti, and the PRIMM Sequencing Facility, for technical support, and Drs. Jean Michel Guys, Armando Cama, Margherita Lerone, Romeo Carrozzo, Victoria Maria Siu, and Hironao Numabe, for clinical evaluation. L.-C. T. is a Senior Scientist, and S.W.S. is a Scholar, of the MRC.