Determinación de PH intraesofágico por 24 horas en niños con reflujo gastroesofágico y asma de reciente diagnóstico tratados con ranitidina

Introduction: Worldwide asthma prevalence is 10% and of GER 8%, therefore coexistence seems to be 1%. Aim: To determine changes in a continuous 24 h intraesophageal pH monitoring test basal and after 4 weeks post treatment with ranitidine in recently diagnosed asthma and GER patients. Methods: 50 children with recently diagnosed asthma according to The American Academy of Asthma Allergology and Immunology criteria, were studied. A basal continuous 24 h intraesophageal pH monitoring test with Digitrapper Mark III equipment and antimony catheter was performed. Children with positive study according to Boyle’s criteria were included and ranitidine treatment (8 mg/kg/day) was initiated. A continuous 24 h intraesophageal pH-monitoring test was performed at 4, 12 and 24 weeks until normalization (negative test).