Pre-treatment Exercise-induced Hypoalgesia is Associated with Change in Pain and Function after Standardized Exercise Therapy in Painful Knee Osteoarthritis

Objectives:Exercise-induced hypoalgesia (EIH), a measure of descending pain inhibitory control, has been found hyperalgesic in subgroups of painful knee osteoarthritis (KOA) patients. The effect of standardized exercise therapy (ET) on clinical pain intensity in KOA has been demonstrated. However, t