Management and analysis of H1N1 close contacts in Guangzhou City.

Objective To analyze the situations of quarantine and management among H1N1 close contacts in Guangzhou city,in order to provide the scientific basis for the prevention and control of H1N1.Methods Close contacts are managed in fixed hospitals and hotels for medical observation.Real-time RT-PCR was used to detect type A H1N1 influenza virus nucleic acid in the throat swabs which were collected in the close contacts who had influenza-like symptoms.Results 223 cases of close contacts were investigated and observed.3 cases of H1N1 positive were found out of 23 cases of close contacts had influenza-like symptoms.The other 220 cases were desegregate.4 H1N1 imported cases were found in quarantined immigrants,and 104 cases of those with close contacts were H1N1 negative.2 H1N1 imported cases were found in the people who went to hospital themselves,and 3 H1N1 positive cases were found out of 60 cases of those with close contacts.And 59 individuals who had close contacts with these 3 cases were H1N1 negative.Conclusion Monitoring the people who have close contacts with the H1N1 patients and finding out infected individuals are the effective measures to control spreading H1N1 influenza.