Effect of a dietary portfolio (nopal, soy, oat, chia seed and inulin) on lipoprotein subclasses and LDL-cholesterol in Mexican subjects with hypercholesterolemia (1035.8)

The use of specific dietary portfolios containing regional functional foods may contribute in a better adherence to the dietary treatment in controlling hypercholesterolemia. We studied the effect of a dietary portfolio (nopal, soy protein, oats, chia seed and inulin) on the concentration of total cholesterol (C), LDL-C, HDL-C and lipoprotein subclasses in 23 Mexican subjects (17 women and 6 men) after three months of dietary treatment. We found a significant decrease in serum LDL cholesterol. This was accompanied with a decrease in the concentration of small LDL particles (p=0.008). In addition, there was an trend to increase serum HDL-C, and it was associated with a significant increase in the concentration of large HDL-particles (p= 0.004). On the other hand, systolic and diastolic blood pressure decreased significantly as well as total body weight and BMI. These results indicate that dietary portfolio intervention could be an important strategy in the prevention of cardiovascular disease by generating...