Enantioselective Formation of Cyano‐Bearing All‐Carbon Quaternary Stereocenters: Copper‐Catalyzed N‐Arylation via Kinetic Resolution.

A copper-catalyzed enantioselective N-arylation for the formation of cyano-bearing all-carbon quaternary stereocenters was developed via kinetic resolution of racemic 3-amino-2-(2-iodobenzyl)propanenitriles. The reaction afforded the desired coupling products in moderate enantioselectivity under catalysis by CuI and a BINOL-derived ligand.