Diagnosis and Classification of ROP

Retinopathy of prematurity (ROP) is a vasoproliferative disease that affects those infants born of the smallest weight and lowest gestational ages. The disease is characterized by its morphology and described as the International Classification of Retinopathy of Prematurity (ICROP). Zone, stage, presence of pre-plus or plus disease and aggressive posterior disease, define the morphology possibly seen during the acute phase of ROP.