Immunohistochemical of diagnostic algorithms neoplastic liver biopsies.

Pathological analysis and evaluation of a liver biopsy is an important step in the diagnosis of single or multiple mass lesions in the liver. Accurate diagnosis is paramount in guiding appropriate treatment. This study conducted a search for liver biopsies for the past 6 years with the diagnostic search codes of neoplasm, metastases, metastatic, adenocarcinoma, neuroendocrine carcinoma, sarcoma, and lymphoma. The aim was to review their pathological workup with a view to developing cost-efficient immunohistochemical diagnostic algorithms. A total of 375 consecutive neoplastic liver biopsies were retrieved and subjected to pathological review. As expected the majority up to 95% of the neoplastic lesions were metastatic lesions.