Pharmacokinetics of human recombinant tissue-type plasminogen activator, administered intra-abdominally, in a rat peritonitis model.

H. van Goor,Vjj Bom,J.W.M. van der Meer,Willem Sluiter,S Geerards,W. van der Schaaf,J.S. Graaff,R.P. Bleichrodt

Pharmacokinetics of human recombinant tissue-type plasminogen activator, administered intra-abdominally, in a rat peritonitis model.

1996

H. van Goor
Vjj Bom
J.W.M. van der Meer
Willem Sluiter
S Geerards
W. van der Schaaf
J.S. Graaff
R.P. Bleichrodt

Human recombinant tissue-type plasminogen activator (rtPA), administered intraperitoneally, may promote intra-abdominal fibrinolysis in peritonitis, thereby preventing adhesion and abscess formation.

Keywords:

Peritonitis
Fibrinolysis
Activator (genetics)
Sepsis
General surgery
Plasminogen activator
Recombinant DNA
Peritoneal fluid
Pharmacokinetics
Pathology
Medicine
Pharmacology
Inflammation

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