Hypertrophic cardiomyopathy: A desensitized cardiac \-adrenergic system in the presence of normal plasma catecholamine concentrations

Only few data are available concerning the biochemical and functional state of the \-adrenergic system in hypertrophied human myocardium. The present study was to investigate the myocardial \-adrenergic signal transduction system in hypertrophic obstructive cardiomyopathy (HOCM).