Clinical characteristics and outcomes of in-hospital cardiac arrest among patients with and without COVID-19

Aims To define outcomes of patients with COVID-19 compared to patients without COVID-19 suffering in-hospital cardiac arrest (IHCA) Materials and methods We performed a single-center retrospective study of IHCA cases Patients with COVID-19 were compared to consecutive patients without COVID-19 from the prior year Return of spontaneous circulation (ROSC), 30-day survival, and cerebral performance category (CPC) at 30-days were assessed Results Fifty-five patients with COVID-19 suffering IHCA were identified and compared to 55 consecutive IHCA patients in 2019 The COVID-19 cohort was more likely to require vasoactive agents (67 3% v 32 7%, p = 0 001), invasive mechanical ventilation (76 4% v 23 6%, p < 0 001), renal replacement therapy (18 2% v 3 6%, p = 0 029) and intensive care unit care (83 6% v 50 9%, p = 0 001) prior to IHCA Patients with COVID-19 had shorter CPR duration (10 min v 22 min, p = 0 002) ROSC (38 2% v 49 1%, p = 0 336) and 30-day survival (20% v 32 7%, p = 0 194) did not differ A 30-day cerebral performance category of 1 or 2 was more common among non-COVID patients (27 3% v 9 1%, p = 0 048) Conclusions Return of spontaneous circulation and 30-day survival were similar between IHCA patients with and without COVID-19 Compared to previously published data, we report greater ROSC and 30-day survival after IHCA in COVID-19