Multilayer aminiotic membrane transplantation plugging comblined with conjunctiva petal with pedicel for corneal ulceration perforation

Objective To evaluate the effect of multilayer amniotic membrane transplantation plugging combined with conjunctiva petal with pedicel for corneal ulceration perforation. Methods Thirty eyes of 30 patients were performed an operation on: including 12 eyes of herpes simplex keratitis of repeated outbreak; 9 eyes of bacterial corneal ulcer perforation; 4 eyes of fungal ulcer perforation;3 eyes of dissolved transplantation graft after keratoplasty;2 eyes of burned corneal perforation.The follow-up conducted for 3 months2years.Results Twenty-eight eyes of patients were healed up but the section of ulceration left behind corneal macula or leucoma.The vision of patients was improved in varying degrees.Two eyes of fungal kemtitis were failed to be operated on penetrating keratoplasty.The efficiency was 93.33%.Conclusions Multilayer amniotic membrane transplantation plugging associated with conjunctival petal with pedicel can preferably cure corneal ulcer perforation caused by various reasons and provide an opportunity for later operation. Key words: Amniotic membrane; Plugging; Transplantation; Corneal ulcer perforation