Alashinols I and J, two novel phenols from stem barks of Syringa pinnatifolia

Abstract Two novel phenols, alashinols I and J (1a and 1b), which are enantiomers, were isolated from the stem bark of Syringa pinnatifolia and possess unusual carbon skeletons. The structures were elucidated based on NMR and MS data analyses, and their absolute configurations were assigned by ECD calculations. Additionally, 1a and 1b were moderately effective at inhibiting oxidative stress-induced injury to H9c2 cardiomyocytes at concentrations of 40 and 80 μM, respectively, and 1a also shown protective effect against hypoxia-induced injury to H9c2 cells at a concentration of 40 μM.