Early-stage ovarian cancer: Clinical outcome and analysis of prognostic factors—Results from a prospective registry of GEICO (Spanish Group for Ovarian Cancer Research).

5582 Background: Early stage ovarian cancer (ESOC) represents 10-15% of all Ovarian Cancer (OC) cases and the reported experience is limited. Methods: A centralized prospective register of ESOC (I-IIb) patients treated at GEICO centers was initiated on January 1998 and updated up to November 2013. Description of cases as well as correlation with Relapse Free Survival (RFS) and Disease Specific Survival (DSS) and an exploratory multivariate analysis was undertaken. Results: A total of 1179 cases with a median age of 48 (17-66) have been included: 983 (83.4%) Stages I, of which 369 (31.3%) were stage Ia, 49 (4,2%) stage Ib and 565 (47.9%) stage Ic, 169 (14,3%) were Stage II and 27 (2.3%) unknown. The most frequent histological type was Endometrioid (E) (n: 320, 27.1%), followed by Serous (S) (n: 297, 25.2%), Clear-cell carcinoma (CCC) (n: 244, 20.7%) and Mucinous (M) (n: 176, 14.9,%). Among E histology grade 1-2 vs grade 3 were present in 19.3% and 5.9% respectively while S grade 1 vs grade 2-3 were 5.9% an...