Mechanical Loading: Potential Preventive and Therapeutic Strategy for Osteoarthritis

Osteoarthritis (OA) is an age-related degenerative disease of the joint, with a hallmark of cartilage degradation.1 No cure or treatment currently exists that offers disease- or symptom-modifying effects. OA is a leading cause of disability, affecting more than 27 million Americans, and it is a significant economic burden.