Assessment of fetal fibronectin concentration in identifying patients at risk for preterm delivery

Identifying patients at risk for preterm delivery continues to be difficult.This study aimed at evaluating fetal fibronectin concentrations in cervical secretions measured by an enzyme-linked immunosorbent assay, as a tool for of premature delivery screening in patients with preterm uterine contractions.Symptomatic 115 women, admitted to Department of Perinatology (RIPMMH) between 24 weeks 0 days and 34 weeks 6 days, with intact amniotic membranes, single pregnancy, cervical dilatation <3 cm and with no cerclage were included. Samples of the cervical secretion were taken every week until the delivery or to hospital discharge.The enzyme-linked immunosorbent assays revealed sensitivity of 73.7% and specificity of 90.9%.This test was found to be a good tool for the prediction of premature delivery.