Respuesta inmune humoral hacia los papilomavirus oncogénicos tipos 16, 31 y 58 en mujeres colombianas con citología normal Humoral Immune Response to Oncogenic Papillomavirus Types 16, 31, and 58 among Colombian Women with Normal Cytology

Objective: To profile IgG and IgA response to the VLP ( virus-like particles) of the human papillomaviruses (HPV) 16, 31 and 58 and to assess the possibility that they may be related to eliminating infection. Methods: A group of 186 women with normal cytology, participants in a cohort study on the natural history of HPV infection, were selected. Three groups were evaluated: control (DNA HPV, n=146 negative), elimination (positive at outset and negative during follow-up, n=25), and persistance (positive during follow-up, n=15).