Efficacy of Crizotinib for Advanced ALK-Rearranged Non-Small-Cell Lung Cancer Patients with Brain Metastasis: A Multicenter, Retrospective Study in China

Puyuan Xing,Shouzheng Wang,Qiang Wang,Di Ma,Xuezhi Hao,Mengzhao Wang,Yan Wang,Li Shan,Tao Xin,Li Liang,Hongge Liang,Yang Du,Zhaohui Zhang,J. Li

Efficacy of Crizotinib for Advanced ALK-Rearranged Non-Small-Cell Lung Cancer Patients with Brain Metastasis: A Multicenter, Retrospective Study in China

2019

Puyuan Xing
Shouzheng Wang
Qiang Wang
Di Ma
Xuezhi Hao
Mengzhao Wang
Yan Wang
Li Shan
Tao Xin
Li Liang
Hongge Liang
Yang Du
Zhaohui Zhang
J. Li

Background The efficacy of crizotinib for anaplastic lymphoma kinase (ALK)-rearranged non-small-cell lung cancer (NSCLC) patients with brain metastasis is controversial. Real-world research data are needed as further evidence.

Keywords:

Brain metastasis
Immunology
Cell
Oncology
Crizotinib
Medicine
Lung cancer
Internal medicine
Retrospective cohort study
Progressive disease
Medical record
Confidence interval
Proportional hazards model

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