[Composition of cerebro-spinal fluid during enflurane anesthesia].

: The compositions of cerebro-spinal fluid (CSF) during enflurane (GOE group; n = 15) and neurolept (NLA group; n = 8) anesthesia were investigated in patients undergoing ventriculo-peritoneal shunt operation. Duration of anesthesia from induction to sampling of CSF was 130 minutes in both groups. Average inhalational concentration of enflurane was 1.6 +/- 0.8%. The concentrations of the electrolytes in CSF and the ratios of them to those in serum were maintained within considerably narrow ranges in both groups without statistical difference. The glucose, protein and osmolarity in CSF or serum were not different between the groups. It is concluded that enflurane does not induce abnormalities in the composition of CSF during clinical anesthesia.