TS and MTHFR gene polymorphisms in patients (pts) with recurrent or metastatic squamous cell carcinoma of the head or neck (SCCHN) treated with pemetrexed (P) and bevacizumab (B)

Marjorie Romkes,T. M. Feinstein,Shilong Zhong,Shama Buch,Michael K. Gibson,K. Skovira,Athanassios Argiris

TS and MTHFR gene polymorphisms in patients (pts) with recurrent or metastatic squamous cell carcinoma of the head or neck (SCCHN) treated with pemetrexed (P) and bevacizumab (B)

2009

Marjorie Romkes
T. M. Feinstein
Shilong Zhong
Shama Buch
Michael K. Gibson
K. Skovira
Athanassios Argiris

e17011 Background: P inhibits multiple enzymes in folate metabolism. We examined polymorphisms in thymidylate synthase (TS) and methylenetetrahydrofolate reductase (MTHFR) in patients with SCCHN tr...

Keywords:

Bevacizumab
Pemetrexed
Carcinoma
Methylenetetrahydrofolate reductase
Cancer research
Medicine
Enzyme
Folate Metabolism
Oncology
Internal medicine
Thymidylate synthase
basal cell
in patient

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