Prostatic carcinoma: Study of C-erb B2, p53, morphological and clinical parameters in 44 radical prostatectomies

In literature it is estimated that only 20% of prostatic carcinoma are clinically important and indicators of biological aggressiveness of the neoplasm would therefore seem necessary. We considered 44 radical prostatectomies that were performed in our Division between 1989 and 1996. A histological section was selected for each patient on which the expression of C-erb B2 and p53 were tested with immunohistochemical methods. In these patients, who were homogeneous as far as surgical criteria are concerned, no subgroups with different progression were found.