ID 199 – Demographic and electrophysiological pattern in Chronic Inflammatory Demyelinating polyradiculoneuropathy among Iranian patients referred to Iran University of Medical Sciences

Objectives There are four basic electrodiagnostic parameters in Chronic Inflammatory Demyelinating polyneuropathy (CIDP): (1) reduced motor conduction velocity (NCV); (2) motor conduction block or abnormal temporal dispersion; (3) prolonged motor distal latency (DL); and (4) prolonged minimal F-wave latency or absent F waves. Methods We retrospectively reviewed the medical records of patients with the clinical diagnosis of CIDP in IRAN university hospitals in 2014 on the basis of a progressive or relapsing polyradiculoneuropathy developing over at least 2 months. Electrophysiological studies were performed with standard surface stimulation and recording techniques. The amplitude, the area under the curve (AREA), and the duration (DUR) of the negative peak of the compound muscle action potential (CMAP) were determined as well as NCV, and DL from the Median, Ulnar, Tibial, and Peroneal nerves in both side. Results prominent observation of the present study is that the frequency of abnormal DL, NCV and Temporal dispersion in Median nerve was more than other nerves. Unequivocal conduction block was more frequent in Peroneal nerve and possible conduction block in Ulnar nerve was more. Conclusion In electrodiagnostinc pattern of CIDP, Median nerve shows more frequent patterns of demyelinatoin Iranian patient. Key words Demyelinating Polyradiculoneuropathy, Conduction Block, Conduction Velocity, Temporal Dispersion, Distal Latency.