Efficient Oral Delivery of Poorly Water-Soluble Drugs Using Carnitine/Organic Cation Transporter 2-Mediated Polymeric Micelles

Chuyu He,Yao Jin,Yunqiang Deng,Yang Zou,Shidi Han,Chuhang Zhou,Yuanhang Zhou,Yan Liu

Efficient Oral Delivery of Poorly Water-Soluble Drugs Using Carnitine/Organic Cation Transporter 2-Mediated Polymeric Micelles

2020

Chuyu He
Yao Jin
Yunqiang Deng
Yang Zou
Shidi Han
Chuhang Zhou
Yuanhang Zhou
Yan Liu

The intestine epithelium is considered to be the most critical obstacle for nanoparticles for oral delivery of water-insoluble and poorly absorbed drugs. Based on the specific transporters located ...

Keywords:

Carnitine
Biochemistry
ORGANIC CATION TRANSPORTER 2
Micelle
Chemistry
Epithelium
Transporter
water soluble
Biophysics
Nanoparticle
Paracellular transport
polymeric micelles

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