Abstract No. 156 Incidence and outcomes of cholecystostomy tubes in COVID-19 patients

Purpose: Our goal was to review the incidence and outcomes of cholecystostomy tube placement during the COVID pandemic as compared to matched controls Materials and Methods: Monthly interventional radiology (IR) case volume was evaluated during the COVID pandemic through July 30, 2020, and was compared to monthly IR case volume during the same time period in 2019 A retrospective review of 40 patients who received percutaneous cholecystostomy tubes between March 2020 and July 2020 (first COVID pandemic peak in Boston, MA) was compared in a propensity matched controlled study 14 COVID-positive patients were matched to 26 control patients who received a cholecystostomy tube Outcomes such as positive cholecystostomy tube microbiology, pre-procedural ICU status, and death were evaluated Results: During March to July 30, 2020, cholecystostomy tube placement constituted 0 43%, average 6 (range 2-10) cases/month of 1389 (range 672-1777) cases/month, whereas in the year prior for the same period it constituted 0 28%, 5 8 (range 4-8) cases/month of 2103 (range 1998-2146) cases/month We find the average age was 66 5 ± 17 7 (SD) for COVID-negative and 66 0 ± 17 7 (SD) years for COVID-positive patients Pre-procedure 19% (5/26) of COVID-negative patients and 50% (7/14) of COVID-positive patients were intubated at the time of placement, P = 0 04 Post-procedure, 54% (14/26) of COVID-negative patients and 50% (7/14) of COVID-positive patients had positive cholecystostomy tube fluid microbiology cultures, P = 0 82 38% (10/26) of COVID-negative patients and 57% (8/14) of COVID-positive patients were in the ICU at the time of placement, P = 0 26 23% (6/26) of the COVID-negative patients and 36% (5/14) of COVID-positive patients died post-procedure, P = 0 41 15 4% (4/26) COVID-negative and 14 3% (2/14) of COVID-positive patients had any complications reported, P = 0 93 Conclusions: During the COVID-19 pandemic, we observed a relative increase in the number of cholecystostomy tube referrals despite a drop in total IR case volume There were no significant differences in post-procedure long-term outcomes and the microbial culture results in our matched control review Our study suggests that this perceived increase in cholecystostomy tube placements is not secondary to unique COVID pathophysiology, but rather a persistent incidence of acalculous cholecystitis in the setting of chronic ICU stays seen during the COVID pandemic With the continuation of the pandemic, cholecystostomy tube placement incidence may increase with continued COVID patient care and chronic ICU stays for these patients