Evidence-Based PET for Cardiac Diseases

This chapter summarizes 15 meta-analyses published in the literature on the use of PET for cardiac diseases, with the majority (n = 8) concerning the diagnosis of coronary artery disease (CAD) using myocardial perfusion imaging (MPI) in comparison to other modalities. Second in the number of published meta-analyses, three studies concentrated on the prognostic value of MPI for adverse cardiovascular events. Finally, one meta-analysis was published on the use of PET for four indications among myocardial viability assessment, the presence of microvascular disease (impaired coronary vascular function in absence of obstructive, epicardial CAD), the use of cardiac hybrid imaging and the diagnostic of cardiac amyloidosis.