Nevoid hyperkeratosis of the nipple mimicking a seborreic keratosis

Nevoid hyperkeratosis of the nipple and or areola NHNA is an uncommon skin disease with an unknown etiology which occurs predominantly in women of child bearing age Initially described in the medical literature by Tauber in as a benign dermatologic change in the nipple and areola Clinically characterized by brown and verrucous thickening which are often bilateral The differential diagnosis of NHNA includes Paget rsquo s disease basal cell carcinoma seborrheic keratosis melanoma erosive adenomatosis and hyperkeratosis secondary to prolonged friction so it rsquo s always considered as diagnosis of exclusion which requires histologic confirmation The therapeutic management is generally justified by the anesthetic discomfort of the patient Various therapeutic modalities have been used with varying success We report a rare case of unilateral Nevoid hyperkeratosis of the nipple clinically and dermoscopically identical to a seborreic keratosis