Influence of the antithrombotic pressure pump on the intracranial pressure of the severe traumatic brain injury patients

Objective To evaluate effect of antithrombotic pressure pump on the intracranial pressure(ICP) of the severe traumatic brain injury(STBI) patients who were performed the surgery. Methods A total of 120 consecutive STBI patients after the surgery, who were admitted at Neurological Intensive Care Units (NICU) from April 2013 to September 2014, were randomly divided into (research group and control group). Each group had 60 patients. In the 6 days observation, research group received the treatment of antithrombotic pressure pump among the first 3 days after the surgery, and the treatment was stopped among the last 3 days. Control group received the opposite treatment. ICP was continuously monitored and all the data (mean ICP, times of ICP ≥20 mmHg, the highest ICP per day) were performed statistical analysis. Results Mean ICP, times of ICP ≥20 mmHg and the highest ICP per day in two groups decreased significantly after the surgery(P<0.05). The difference of Mean ICP, times of ICP ≥20 mmHg and the highest ICP per day between the two groups were not significant. No patient got the deep vein thrombosis (DVT). Conclusions Antithrombotic pressure pump could efficiently prevent deep vein thrombosis, which is a safe treatment for STBI patients and has no influence on the ICP. Key words: Severe traumatic brain injury; Intracrainal pressure; Deep vein thrombosis; Antithrombotic pressure pump