Reduced High-Mobility Group Box 1 Expression Induced by RNA Interference Inhibits the Bioactivity of Hepatocellular Carcinoma Cell Line HCCLM3

Wei Jiang,Zhiming Wang,Xinying Li,Jindong Li,Yun Huang,Xue-Gong Fan,Yankun Duan

Reduced High-Mobility Group Box 1 Expression Induced by RNA Interference Inhibits the Bioactivity of Hepatocellular Carcinoma Cell Line HCCLM3

2012

Wei Jiang
Zhiming Wang
Xinying Li
Jindong Li
Yun Huang
Xue-Gong Fan
Yankun Duan

Background Increased expression of high-mobility group box 1 (HMGB1) has been observed in many tumor types, but the role of HMGB1 in hepatocellular carcinoma (HCC) is unknown.

Keywords:

High-mobility group
Medicine
Hepatocellular carcinoma
RNA interference
HMGB1
Molecular biology
Cell culture
Transplant surgery
hepatic carcinoma

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