Mandibular ameloblastoma with papillary hyperplasia in the gingiva: A case report

Abstract Although ameloblastomas are relatively common tumors, they rarely occur in the gingiva or oral mucosa. Most gingival or oral ameloblastomas are peripheral (that is, soft-tissue) ameloblastomas; therefore, an exophytic peripheral lesion from an intraosseous ameloblastoma is unusual. Here, we report a 63-year-old man who had an ameloblastoma with papillomatous proliferation in the lingual gingiva. Magnetic resonance imaging showed a well-defined mass in the mandible. These tumors were enucleated intraorally under general anesthesia. Histopathological and immunohistochemical examinations revealed that the respective tumors were a papilloma and an ameloblastoma, with different origins. The histopathological diagnosis was an intraosseous ameloblastoma with papillary hyperplasia. The patient’s postoperative course was uneventful during his 20-month post-enucleation follow-up period.