Ultrastructure of human aneuploid spermatozoa

: The goal of the study was to evaluate ultrastructural changes in aneuploid human spermatozoa. The sperm was collected from seven males with teratozoospermia. In all patients ultrastructural changes in spermatozoa were noted: inappropriate nuclear chromatin condensation, changes in the formation of the acrosome and pathology of the mobile apparatus. These changes suggest a defect in spermatogenesis at the level of spermatide or spermatocyte. Ultrastructural spermatozoa studies may reveal new elements related to factors responsible for decreased sperm fertilizing ability.