Effect of a Polymorphonuclear Elastase Inhibitor (Sivelestat Sodium) on Acute Lung Injury After Cardiopulmonary Bypass: Findings of a Double-Blind Randomized Study

Masahiro Ryugo,Yoshiki Sawa,Hiroshi Takano,Goro Matsumiya,Shigemitsu Iwai,Masamichi Ono,Hiroki Hata,Takashi Yamauchi,Masaji Nishimura,Yuji Fujino,Hikaru Matsuda

Effect of a Polymorphonuclear Elastase Inhibitor (Sivelestat Sodium) on Acute Lung Injury After Cardiopulmonary Bypass: Findings of a Double-Blind Randomized Study

2006

Masahiro Ryugo
Yoshiki Sawa
Hiroshi Takano
Goro Matsumiya
Shigemitsu Iwai
Masamichi Ono
Hiroki Hata
Takashi Yamauchi
Masaji Nishimura
Yuji Fujino
Hikaru Matsuda

Purpose We evaluated the effect of sivelestat sodium (SiV), a novel synthesized polymorphonuclear (PMN) elastase inhibitor, on acute lung injury (ALI) caused by cardiopulmonary bypass (CPB).

Keywords:

Systemic inflammatory response syndrome
Randomized controlled trial
Elastase inhibitor
SIVELESTAT SODIUM
Cardiopulmonary bypass
Intensive care unit
Postperfusion syndrome
Lung
Medicine
Anesthesia
Surgery
lung injury
Polymorphonuclear Elastase

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