PRIMARY INTRAOSSEOUS SQUAMOUS CELL CARCINOMA OF THE MANDIBLE: A RARE CASE REPORT

The primary intraosseous squamous cell carcinoma (PISCC) is a rare malignant neoplasm of epithelial origin that affects the jaw bone interior without affecting the oral mucosa in a primary way. A 66-year-old male patient presented an intraoral volume increase, with coloring similar to the mucosa, hardened consistency, and painful symptoms located in the mandibular body left side. The radiographic examination showed a unilocular radiolucent image with poorly defined limits associated with the mandibular fracture. An incisional biopsy was performed, and the histopathologic examination demonstrated a malignant neoplasm of epithelial origin characterized by the proliferation of pleomorphic cells organized in sheets, nests, and cords and were also dispersed in a fibrous connective tissue stroma. Malignant neoplasms were discarded in other sites, and the diagnosis of PISCC was established. The patient underwent complete surgical resection of the lesion and is currently being followed up after 6 months without clinical-radiographic signs of relapse.