Nitric oxide synthase activator

【Task】 The present invention, nitric oxide synthase activators, as well, it is an object to find the method of administration and dosage. A Midkine family protein or nitric oxide synthase activator containing a midkine derivative as an active ingredient. In particular, blood, intracoronary, or, characterized in that it is administered intravenously, nitric oxide synthase activators like which comprises, as an active ingredient a midkine family protein or a midkine derivative. .BACKGROUND