Experience of laboratorians participation in the treatment of complex pulmonary multidrug resistant bacteria infection

Objective To discuss the role of laboratorians in the treatment of complex multidrug-resistant bacteria. Methods One laboratorians participated in the treatment of one patient admitted in Yixing No. 2 People’s Hospital on May 20th 2017 who was infected by Klebsiella pneumoniae carrying Extended-spectrum β-lactamases (ESBLs), Mycoplasma pneumonia and extensively drug resistant Acinetobacter Bauman. Treatment was provided to clinicians and the clinical efficacy was evaluated. Results According to the drug sensitivity results and drug resistance mechanism analysis, the laboratorians suggested that high dose imipenem (intravenous drip 1.0 g every 6 hours) should be used and the drip time should be prolonged to 2-3 hours. The patient had no fever, cough and asthma after treatment. Blood routine and other indicators returned to normal, and bacterial culture was negative. Conclusions Laboratorians participating in clinical anti-infection treatment, and providing reasonable advice for clinicians could improve clinical cure rate of complex multidrug-resistant bacteria infection. Key words: Extended-Spectrum-β-lactamases; Extensively drug resistant Acinetobacter baumannii; Anti-infective therapy