cPAS-based sequencing on the BGISEQ-500 to explore small non-coding RNAs

Tobias Fehlmann,Stefanie Reinheimer,Chunyu Geng,Xiaoshan Su,Snezana Drmanac,Andrei Alexeev,Chunyan Zhang,Christina Backes,Nicole Ludwig,Martin Hart,Dan An,Zhenzhen Zhu,Chongjun Xu,Ao Chen,Ming Ni,Jian Liu,Yuxiang Li,Matthew Poulter,Yongping Li,Cord Stähler,Radoje Drmanac,Xun Xu,Eckart Meese,Andreas Keller

cPAS-based sequencing on the BGISEQ-500 to explore small non-coding RNAs

2016

Background We present the first sequencing data using the combinatorial probe-anchor synthesis (cPAS)-based BGISEQ-500 sequencer. Applying cPAS, we investigated the repertoire of human small non-coding RNAs and compared it to other techniques.

Keywords:

Genetics
DNA sequencing
Exome sequencing
Human genetics
microRNA
Bioinformatics
Biology
Biomarker discovery
Gene expression profiling
Human genome
median correlation
DNA microarray
MiRBase

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