Same-day discharge after catheter ablation in patients with atrial fibrillation in a large nationwide administrative claims database.

Background Catheter ablation (CA) is a common treatment for atrial fibrillation (AF). This study evaluated outcomes of same day discharge (SDD) versus overnight stay (ONS) among AF patients undergoing outpatient CA. Methods The Optum SES Clinformatics Extended Data Mart database was used to identify patients ≥18 years of age undergoing outpatient CA for AF (2016-2020). Eligible patients were indexed to the date of first CA and classified into SDD and ONS groups based on the length of service. A 1:3 propensity score matching was used to create comparable SDD:ONS samples. The primary safety outcome was CA-related complications within 30 days of index procedure. The primary efficacy outcome was AF recurrence within one year. Cox proportional hazards models were estimated for outcome comparison. Results In the post-match 30-day cohort for safety evaluation, there were 6,600 patients (1,660 [25.2%] SDD; 4940 [74.8%] ONS), with a mean age of 66.6 years. There was no significant difference in the 30-day composite rate of post-ablation complications (4.7% [78/1660] vs. 3.8% [187/4940]; p=0.100) and 1-year composite rate of AF recurrence (14.3% [142/996] vs. 14.5% [430/2972]; p=0.705) between the SDD and ONS groups. Conclusion This study demonstrated that SDD following CA to treat patients with AF is safe, with low rates of post-ablation complications and AF recurrence, which were comparable to rates in patients with an ONS after CA. This article is protected by copyright. All rights reserved.