Biogenic silver nanoparticle synthesis with cyanobacterium Chroococcus minutus isolated from Baliharachandi sea-mouth, Odisha, and in vitro antibacterial activity

Abstract The burden from microbial diseases has to be addressed in an increasing pace due to multidrug resistance, causing clinical annoyance, globally. Indeed, employing eco-friendly approaches by green syntheses of nanoparticles with metals/metalloids as antibacterial compounds would be continual and cost-effective. Herein, the synthesis of silver nanoparticles (AgNPs) by aqueous extracts of the cyanobacterium Chroococcus minutus (strain, CRLSUM10), collected from the meeting point of sea and river, East coast of India, are presented; both reducing and stabilizing mediators of the synthesized AgNPs were ascertained, by characteriztion by UV-visible spectrophotometry, XRD, FTIR, SEM and SEM-EDX. Furthermore, synthesized AgNPs had a remarkable antibacterial activity at the lowest dose, 100 mg against pathogenic strains of E. coli and S. pyogenes, rendering those as novel antibacterial agents against ‘upper respiratory tract infection’.