National multi-center study on chemotherapy safety practice

17569 Background: Safety practice is an important quality indicator of cancer care. Given the potential toxicity of chemotherapy (CT), the safety practices of intravenous (IV) CT for cancer have received little attention. The purpose of this study was to characterize the safety practices of prescribing IV CT and examine their association with the adverse drug events (ADR) after CT in Taiwan. Methods: A total sample of 948 medical records of newly diagnosed breast (BC), lung (LC), colon-rectal (CRC) and oral cancer (OC) were drawn via proportional probability random sampling from 7 medical centers across the Taiwan. Using data from reviewing the medical records, the safety practices were measured as characteristics of prescribing IV CT, including record of protocol name, format of prescriptions, calculation of dosage and double checking. Near-miss prescription (NM) was determined as percentage of inconsistent, unrecognized recordings about the CT regiments throughout the CT course, or unreadable prescripti...