A Case of Carbapenem Resistant Non-K1/K2 Serotype Klebsiella pneumoniae Liver Abscess
2013
Klebsiella pneumoniae liver abscess (KPLA) has been described as an invasive syndrome with extrahepatic
complications. The majority of KPLA is caused by capsular serotype K1 and K2 isolates. We report a case of carbapenem resistant Klebsiella pneumoniae liver abscess. The patient initially presented with
infected right above-the-knee amputation and was later found with a
large liver abscess.
Initial antimicrobial susceptibility showed carbapenem resistant K. pneumoniae (CRKP). Further molecular workup
revealed that the isolate
was a less virulent non-K1/K2 serotype, and both rmpA and kfu genes were negative. The lack of outer membrane porins likely contributed to the carbapenem
resistance. To
our knowledge, this is a first reported case of carbapenem resistant, non-K1/K2 serotype K. pneumoniae liver abscess in the United States.
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