Randomized Clinical Trial Comparing Mitoxantrone with Epirubicin and with Doxorubicin, each Combined with Cyclophosphamide in the First-Line Treatment of Patients with Metastatic Breast Cancer

E. Heidemann,B. Steinke,J. H. Hartlapp,K. Schumacher,K. Possinger,S. Kunz,E. Neeser,G.v. Ingersleben,D. K. Hossfeld,R. Waldmann

Randomized Clinical Trial Comparing Mitoxantrone with Epirubicin and with Doxorubicin, each Combined with Cyclophosphamide in the First-Line Treatment of Patients with Metastatic Breast Cancer

1990

E. Heidemann
B. Steinke
J. H. Hartlapp
K. Schumacher
K. Possinger
S. Kunz
E. Neeser
G.v. Ingersleben
D. K. Hossfeld
R. Waldmann

Two hundred and twenty-four patients with advanced breast cancer were enrolled in a multicenter prospective randomized clinical study and received either doxorubicin (40 mg/m2), or epirubic

Keywords:

Breast cancer
Randomized controlled trial
Doxorubicin
Mitoxantrone
Progressive disease
Oncology
Epirubicin
Metastatic breast cancer
Internal medicine
Cyclophosphamide
Medicine
Cancer

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