Prospective cohort of chronic diseases among urban residents in Guangdong Province: design and baseline characteristics of subjects from 2018 to 2019

Objective  To explore the distribution of health relative factors and further reveal the epidemic characteristics and incidence of chronic diseases among urban residents in Guangdong Province. Methods  From March 1, 2018 to October 30, 2019, a baseline survey was conducted in Guangzhou, Dongguan and Shenzhen of Guangdong Province, including questionnaire, physical examination, biological sample collection and laboratory test. A cohort baseline database and a biobank of 34 764 subjects aged 30 to 84 were established. Results  34 764 participants with age of (53.31±12.61) years including 41.1% males, were recruited in this study. The prevalence of current smoking was 34.4% in men and 0.4% in women. The prevalence of current regular alcohol drinking was 16.7% in men and 1.9% in women. The proportion of participants whose BMI ≥24 kg/m2 was 54.4% in men and 44.4% in women. 35.8% of males had a waist circumference greater than 90 cm, while 34.0% of females had a waist cir-cumference greater than 85 cm. The proportion of participants who were hypertensive (SBP ≥140 mm Hg or DBP ≥90 mm Hg) was 34.8% in men and 28.8% in women. Conclusions  The factors related to chronic diseases, such as diet, smoking, drinking and obesity, showed different distribution of characteristics among urban residents in Guangdong Province of different genders and ages.