Flow-Assisted Synthesis of Heterocycles via Multicomponent Reactions

Multicomponent reactions (MCRs) are of great significance in organic synthesis. They often decrease the number of synthesis steps since three or more reactants are incorporated in the product in a single step. This increases the number of combinatorial options and allows more efficient processes in less time. The pharmaceutical industry is therefore very fond of MCRs for the construction of libraries. As a consequence, the field is being investigated intensely for the enhancement of chemical processes and the discovery of new types of MCRs.